Recently, the National Institute of Health has funded a center at the University of Missouri focused on evaluating gene editing (GE) methods and outcomes in swine animal models. Current projects are targeting genes related to vision, hearing, brain and neuron function; other projects are focused on genes involved in diseases and functions of the lung and bone marrow. The Senior Research Associate is a member of the Swine Somatic Cell Gene Editing Testing Center. Their role involves the evaluation of animals' physiological and immunological responses to gene editing reagents or to the altered genes themselves. This person's primary roles are expected to involve: coordinating projects and implementing delivery of reagents to pigs; immunohistochemistry of target proteins; toxicology screens; and the implementation of immunoassays/cell-based assays to measure inflammatory responses in the test animals. The person may also participate in projects designed to produce pig models that mirror human disease states. Related efforts would be focused on the production of GE reagents intended to correct or modify mutant or disease-associated alleles. The candidate will utilize multiple technology platforms, including thermocyclers, visible/fluorescent/luminescent plate readers, light/fluorescent/confocal microscopy, and flow cytometry. This position will also manage tissue/sample collections for the transfer, development, validation, and execution of assays performed elsewhere.
Major Responsibilities:
Supervision:
Minimum Qualification: MS in Biological Sciences or related field required at the time of application.
Candidates will be evaluated on:
Apply online at , Job ID# 48872, and upload the following documents:
1) Cover Letter
2) CV
3) Reference List
Review of applications will begin once received and continue until the position is filled.
Contact: Please direct questions to Addison Byrne via email - ByrneAK@missouri.edu.
This position is eligible for University benefits. The University offers a comprehensive benefits package, including medical, dental and vision plans, retirement, and educational fee discounts. For additional information on University benefits, please visit the Faculty & Staff Benefits website at
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